瑞士巴塞尔大区经济及创新促进局欢迎您

在瑞士最具活力的经济地区培育创新,加速业务发展  >>>>

最瑞士

瑞士是亲商、可靠和高效的代表。巴塞尔地区经济强盛,秉承明确的亲商核心价值,是瑞士这些美德的光辉榜样。  >>>>

生命科学和医疗行业第一

整个生命科学价值链汇聚于一处,且触手可及?这是600家及越来越多的公司对巴塞尔地区情有独钟,将其作为研发、生产和总部的原因。  >>>>

创新行业第一

多项研究结果表明,瑞士是全球最具创新精神的国家。巴塞尔地区丰富的知识、高素质国际人才和强有力的产业支柱使瑞士成为领先的创新枢纽。  >>>>

往来欧洲交通便利度第一

无论是集装箱运输还是空运,巴塞尔地区都拥有交通便利的优势。它与德国和法国接壤,位于欧洲中部的中心地带,是国际贸易青睐的物流枢纽和城市平台。  >>>>

文化和休闲第一

世界级艺术珍宝、文化和体育活动,融入健康自然娱乐景观中的国际化都市氛围,所有这些因素结合在一起,使巴塞尔地区成为全球最适宜居住和工作的地区之一。  >>>>

瑞士巴塞尔大区经济及创新促进局是瑞士西北地区巴塞尔乡村州、巴塞尔城市州和汝拉州为促进创新和经济发展而联合成立的机构。本机构旨在帮助国外企业家和公司在巴塞尔地区成功实践创新,创立公司。

我们拥有15,000名决策者、创新者、专家、影响者和增值者组成的广泛关系网络,让客户能直接获取相关专业知识和技术。

瑞士巴塞尔大区经济及创新促进局主要在以下四个领域内为客户提供定制化服务:

  • 投资巴塞尔地区:提供个性化支持,帮助客户在巴塞尔地区择址。本机构将在整个择址和入驻过程中为公司提供中肯的建议。
  • 为创新着牵线搭桥:帮助生命科学、医疗技术、信息通信技术(ICT)、微技术、纳米及材料和生产技术领域的公司和研究人员在技术、研发和创新事务方面建立联系。
  • 支持创业:为计划在巴塞尔创业的企业家提供全面支持,在其商业计划的运营执行过程中进行协助。此外,以上技术领域中处于扩张模式的初创公司和中小型公司可从策略性交流服务中受益,与行业专家和投资人建立联系。
  • 进驻中国:为瑞士西北部地区寻求扩张到中国的公司提供适当的合作伙伴网络,协助其顺利进驻中国市场,执行扩张项目。

瑞士巴塞尔大区经济及创新促进局还管理着一个综合性信息平台,展示巴塞尔商业地区的优势和专长领域,进一步促进该区域创新公司的融入:

  • “创新报告”:涵盖巴塞尔地区最新创意活动和报告,每月发布一次新闻简报,内容包含采访、背景故事和公司入驻本地的消息。
  • “创新活动”:瑞士巴塞尔大区经济及创新促进局每年组织并合办逾50次专门针对知识转移和创业文化的活动。在“创新活动”中,创新者和企业家分享他们最新的创新理念和经验。

在竞争力和创新能力方面,瑞士已多年位居世界顶级营商目的地前列。多个因素保证了瑞士的领先地位。除了优良的教育和先进的基础设施外,让瑞士等同于亲商、可靠和高效的另一个重要原因就是高效的瑞士政府机构。几十年来,瑞士强有力的法律系统、可靠的规划和稳定的金融体系使得在瑞士经营的公司及其在这里的投资项目都受益匪浅。这种环境也是企业向新市场持续扩张的一个最重要的前提条件。瑞士跨国公司密度全球最高绝非偶然。

巴塞尔地区对瑞士的成功做出了重大贡献。众多国际领先跨国公司不仅发迹于此,这些公司的成功也为该地区的经济增长注入强劲动力。例如,巴塞尔地区的GDP远高于瑞士全国平均水平。大巴塞尔地区人均国内生产总值为瑞士最高。与此同时,巴塞尔在生命科学和其他高科技领域的领先优势推动了瑞士创新能力的发展。例如,瑞士约有占总值五分之一的出口货物在巴塞尔地区制造,考虑到巴塞尔地区人口仅占瑞士人口不到10%,这是十分了不起的成就。

在全球商业、产业和知识竞争力方面,瑞士,特别是巴塞尔地区享有的美誉主要体现在以下四个突出优势上:

  • 明智的税收政策:瑞士采用的联邦制度鼓励州与州之间的财政竞争,使税收保持在合理的范围内。除了联邦层面的统一税率外,各州可自主确定税率,并为公司提供最佳的营商环境。由此,巴塞尔地区的主要受益人是活跃在创新行业、具有高附加值的公司,以及大力投资研发和生产的公司。
  • 自由的劳力市场:由于巴塞尔地区拥有众多活跃于国际的高科技公司,地方政府对于他们对海外高素质专家和高级管理人员的需求采取支持态度。这一欧洲最自由的劳动市场之一使得企业从中受益,同时也给予员工巨大利益。巴塞尔地区的劳动法规和劳力市场使得公司可以在营商环境发生变化并需采取相应措施时能够做出快速反应。
  • 可持续的基础设施:在瑞士,火车晚点5分钟就会令人不快,但这种情况极少发生。这一点常令外国访客露出满意的笑容。众所周知,瑞士的公共基础设施堪称世界上最先进、最可靠的,而巴塞尔地区的优势正在于此。交通四通八达,通过公路、铁路和飞机航线可往返欧洲各地,通过莱茵河的水路可通向全球。
  • 双轨制教育体系:瑞士仅三分之一的年轻人高中毕业后选择继续在瑞士顶尖大学深造。对于很多国家来说,这也许是教育体系的重大失职。但是实际上,这是瑞士在专业技术上成功的一部分原因。瑞士双轨制教育体系旨在确保大多数年轻人完成瑞士联邦认证的学徒期,以尽早参加工作。年轻人可以(也通常会)在瑞士技术学院或应用科学类大学获取专业学位,大多是在职学位。这为瑞士劳力市场稳定提供了经过多年在职培训的入门级雇员,这些人员可以在最具发展潜力的行业进行灵活就业,而雇主和行业实际上也需要这样的人才。此外巴塞尔地区的独特优势在于其拥有众多完善的国际学校,这些学校能够满足外籍人士及其子女的需求,帮助他们轻松融入当地。

作为唯一一个基于直接民主制的政治体系,瑞士在几百年里建立起独特的具有凝聚力的政治和社会文化。其特点是联邦制、自治和一致性,是稳定的政治和社会环境的基石,也是瑞士价值观的体现。巴塞尔地区政府及其民众的开放思想和进取态度,使其成为营商目的地的典范,为企业提供了优良的发展环境,推动企业不断发展壮大。

巴塞尔地区是生命科学领域全球最受欢迎的目的地之一,在欧洲更是无出其右。作为全球市场前三强的罗氏和诺华都是从巴塞尔地区起家,继而将业务拓展至全球。

与之类似的其他跨国公司也在巴塞尔建立了其中心业务分部,其中包括礼来、雅培和拜耳。Actelion、Basilea和Evolva等众多新入驻的公司以及Bachem和Polyphor这样高度专业化的公司使得巴塞尔形成完整的生命科学生态系统。并不令人意外的是,巴塞尔地区还演变成具有发展前景的初创公司钟爱的热点地区。

巴塞尔地区有共计600家生命科学公司,它们对该地区业已颇具活力的营商环境做出重大贡献。这些企业的持续成功主要基于以下三个因素:

  • 生命科学行业是巴塞尔地区经济增长的引擎。这个行业在此生根发芽,且枝繁叶茂:巴塞尔地区生命科学行业的雇员共计2.7万名,每小时生产的产品和服务价值高达3.01亿美元。这使巴塞尔地区成为全球生产力最高的生命科学目的地。巴塞尔地区的生产总值也位居全球之冠:巴塞尔地区的产量全球最高,年产值达130亿美元。与此同时,巴塞尔地区每年获得90亿美元研发投资,是全球这方面数额最高的地区。本地生命科学使经济增长高于瑞士全国平均水平,这使得该行业在巴塞尔地区的声誉无可挑剔。
  • 巴塞尔地区拥有各类人才和专家,而且人数众多:从研发、创办公司到制造、营销和分销,巴塞尔地区拥有一条完整的生命科学价值链,因此您能找到企业在各个发展阶段和各个职能所需的人才和专家。他们人数众多,且经验丰富。加上顶尖的研究机构,如巴塞尔大学生物研究中心(Biozentrum)、苏黎世联邦理工学院(ETHZ)生物系统科学与工程学院和弗雷德里希•米歇尔研究所(FMI),您大致可以了解到巴塞尔地区独特的生命科学资源组合的范围有多广。该地区有触手可及的资源、技术和人才,其深度和密度在全球范围都无可匹敌。这为未来创新提供了独一无二的肥沃土壤。
  • 巴塞尔地区作为生命科学行业的创新标杆已有逾250年的历史:因此巴塞尔地区可谓是涉足生命科学领域历史最悠久的地区。从十九世纪中叶的工业丝带染坊到生物技术革命,巴塞尔的生命科学生态系统不断演进,并在行业的巨大发展中实现了自身突破。这一光辉故事将被续写。与其他曾经实现发展的生命科学中心不同的是,巴塞尔地区在过去几年一直保持稳定和持续的增长。该地区未来几年计划在公共和私人基础设施项目上将投入70亿瑞士法郎,因此下一个高增长期指日可待。

传统优势、强有力的产业支柱、深厚的研发和商业化专长,使得巴塞尔地区成为全球最为完善和成熟的生命科学目的地。您很难再找到另一个像巴塞尔这样适合在生命科学领域高效、可持续和成功地开发科研及商业项目的地区。

高科技是巴塞尔地区经济的推动力,并且是本地经济增长高于平均水平的保障。而且这种局势将持续下去。强有力的产业支柱、吸引全球人才和专家的国际化营商环境,加上瑞士世界一流的教育体系,使巴塞尔地区成为创新的理想环境。在这里,企业,尤其是医疗技术、信息与通信技术、精密机械以及化工业公司都将从该地区的以下特点中受益:                       

  • 巴塞尔地区拥有深厚的高科技产业基础:巴塞尔城市州92%的产业附加值来自高科技公司。类似地,在巴塞尔乡村州和汝拉州,该比例远高于70%,因此高于瑞士60%的平均水平。而瑞士60%的平均水平已使其跻身于世界最具创新精神的国家之列。
  • 巴塞尔地区是研发领域领头羊:瑞士私营部门的研发投资比例高达69%,在全球范围内都属于较高比重。其中40%来自巴塞尔地区,而本地人口仅占瑞士人口的10%。瑞士国内专利最多的十家公司中有五家的总部位于巴塞尔地区,它们是罗氏、诺华、科莱恩、先正达和Endress+Hauser。这也是为什么巴塞尔地区成为瑞士国内聘请研发人员最多的地区。
  • 巴塞尔地区与全球紧密联系,吸引着世界各地的人才:巴塞尔70万居民中约有五分之一来自海外;当前外籍人士达到3.6万人。巴塞尔地区与德法两国接壤,每天有7万名跨境上班族从邻国流入。很难再找到一个地区,像巴塞尔地区这样在如此小的区域内拥有如此具有活力的国际商务氛围,并吸引着全球各地的专业人才汇聚一处。
  • 世界一流的科学和学术教育:除了是强大的产业研发中心外,巴塞尔地区在欧洲学术界举足轻重。巴塞尔大学拥有2,000名教授和1.2万名学生,是欧洲历史最悠久的大学之一,位居全球100所大学之列。从巴塞尔地区乘火车,2小时内即可到达苏黎世联邦理工学院(ETHZ,在巴塞尔设有生命科学学院)和洛桑理工学院(EPFL)。这两所大学都是全球绝对一流的大学。巴塞尔地区(包括其交界国)数百公里范围内共有167家研究机构。此外,瑞士的双轨制教育体系和瑞士西北应用科学大学稳定提供训练有素的高技能专业人才。

研究和调查结果显示,瑞士多年来一直都是全球领先的创新地区之一。强有力的产业支柱、吸引全球人才的全面国际化营商环境,再加上瑞士学术和双轨教育体系,使巴塞尔成为瑞士的创新枢纽。巴塞尔地区的资源密度可谓独一无二:在巴塞尔地区,最高水平的科学表现、行业专长和技术,以及高素质的劳动力都触手可及。


早在罗马帝国时期,巴塞尔莱茵港口就是通向北海航道的最南端港口。1226年,博登湖和北海之间的莱茵河段上建成第一座桥梁(也是此后多年唯一一座),使得巴塞尔演变为重要的贸易枢纽。巴塞尔地区与德国和法国接壤,位于欧洲中部的中心地带,保持了其作为瑞士最重要交通和物流枢纽的领先地位,为本地产业和商业带来诸多利益。
此外,巴塞尔地区特别适合计划在欧洲建立全球总部,以及积极追求全球贸易新机遇的公司。巴塞尔地区具有以下独特优势:

  • 巴塞尔地区是欧洲重要的交通枢纽:从市中心乘出租车或公交仅需15分钟即可到达巴塞尔机场。从该机场可到达欧洲、北美和中东的90多个目的地。集装箱从巴塞尔城的三个莱茵河港口发出,三天内可到达鹿特丹港,而后从那里运往全球各地。火车站每个小时就有一列开往瑞士所有主要城市的火车,如苏黎世(包括苏黎世国际机场)、伯尔尼、洛桑和日内瓦,以及莱茵河畔的各个经济中心(即弗莱堡、卡尔斯鲁厄和斯特拉斯堡)。乘坐高铁几个小时就可轻松便捷地到达欧洲各大都市和首都,如法兰克福、巴黎和米兰。
  • 巴塞尔地区是瑞士领先的物流枢纽:巴塞尔的三个莱茵河港口吞吐量占瑞士外贸总量的12%,其中食品和农产品吞吐量高达84.2万吨。整个巴塞尔地区的外贸额占瑞士总量的三分之一。巴塞尔机场是瑞士领先的货运机场。这使得巴塞尔作为物流枢纽的地位名副其实。巴塞尔物流行业拥有2.3万名从业人员。990家物流公司落户巴塞尔地区,包括市场领导者DHL、Panalpina、Goldrand 和嘉里物流。这些公司可提供成熟的解决方案应对复杂挑战,例如在供应链管理方面,而这正是生命科学和化工业企业常常需要的。
  • 巴塞尔地处欧洲中心位置,是国际贸易公司的理想之选:特种烟草制造商大卫杜夫、零售商Dufry、餐饮公司 Transgourmet 和国际清算银行等各类公司和机构凸显出在巴塞尔交易和提供的货品的多样性。因此瑞士第二大连锁超市Coop和第一大百货公司Manor都选择将总部设在巴塞尔地区。该地区同样是一系列国际贸易展会的重要举办地。每年举办的巴塞尔国际钟表珠宝展(BaselWorld)实现了国际名表和珠宝业的很大一部分销售额。而巴塞尔艺术博览会(Art Basel)则是全球最重要的艺术盛会。越来越多的国际消费品牌已发现巴塞尔作为贸易枢纽的优势,并将欧洲总部设在巴塞尔地区。其中就有美国著名时尚品牌Fossil、自行车制造商Cannondale和时装设计品牌Tally Weijl。

越来越多的跨国公司发现将巴塞尔作为其全球或欧洲总部的吸引力,特别是考虑到巴塞尔出色的连通性和运输系统以及本地在物流和国际贸易上的优势。老字号瑞士公司和初创公司都在利用这里处于欧洲中心所带来的优势。最后,巴塞尔地区毗邻德国和法国,与世界各地交流频繁,本地人口具有世界性,使得整个商业区域生机勃勃,持续增长。

早餐在德国,中餐在法国,晚餐在瑞士:巴塞尔地区地处三国交界处,具备都市化的国际商业氛围,与瑞士其他都市地区相比,人们可以以相对较低的成本享受无与伦比的生活品质。获奖建筑、历史悠久的市中心和从嬉皮士到经典风格的丰富精致的文化生活,都是巴塞尔地区良好城市生活方式的几大支柱。同时,成熟的公共交通系统可快速直达郊区和乡村居住区,以及那里的自然公园和休闲场所。

问一问新来者和新移民:巴塞尔不仅拥有瑞士最大的外籍人士社区,各种国际学校为他们的子女提供教育,而且是定居时间超过5年外籍人士比例最高的地区。原因不止一个:

  • 每个人都能享有巴塞尔的城市生活方式和丰富的文化生活:巴塞尔的根基在罗马和凯尔特人时期就已打下。中世纪末尾至现代初期,该地区首次达到全盛。当然,巴塞尔并未止步于此。现今,巴塞尔繁荣的创意行业、各色当地美味餐馆,以及丰富的文化活动带来了生机勃勃的都市生活方式。在狂欢节时漫步风景如画、历史悠久的市中心,在新巴洛克风格的交响乐厅前停留,或在夏季到明斯特广场观赏户外电影——巴塞尔总是精彩不断。
  • 到了巴塞尔,艺术爱好者就来对了地方:巴塞尔美术馆创立于1671年,被视作历史最悠久的公共社区艺术博物馆。根据伦敦泰晤士报的排名,该馆位列世界5大美术馆之一。另一吸引人的景点是拜尔勒基金会博物馆。该馆由意大利著名建筑师Renzo Piano设计。巴塞尔的另一个艺术重头戏是全球最大的艺术展——巴塞尔艺术博览会(Art Basel)。每年,艺术家、收藏家、画廊和拍卖行以及名流贵宾早早地就在日历里标出博览会举办的日期。他们中有些人会赶来欣赏巴塞尔剧院享誉全球的获奖演出(有歌剧、戏剧和芭蕾舞)。
  • 巴塞尔地区总是充满了运动气息,而且不仅是在体育馆或沙发前的电机上:本地最受欢迎的巴塞尔足球俱乐部(FC Basel)在圣雅各布公园主场迎战欧洲足球顶尖赛事的对手。ATP巡回赛的一流选手参加瑞士室内网球锦标赛,其中包括本地超级球星罗杰·费德勒。在竞技场之外,巴塞尔民众也很热衷于运动。巴塞尔地区自行车使用率为全瑞士最高,包括骑车的上班族和在周边乡间无数自行车道上行进的骑行爱好者。跑步爱好者可在莱茵河两岸的无障碍通道跑步。越野滑雪爱好者可在汝拉州绵延数公里的缓坡上滑行。驱车2小时不到,高山滑雪者和雪板滑雪者就可达到瑞士阿尔卑斯山的原始山坡上。
  • 在瑞士、德国和法国交界处,有各色吸引人的活动等着您:是参加阿尔萨斯的品酒会、巴登-符腾堡南部的美食盛宴,还是在汝拉州山峰上惬意地野餐?在巴塞尔地区,没有一小时车程里满足不了的需求。而且,总会有新发现!想在炎炎夏日跳进沁凉的河水中吗?这时,莱茵河岸线将成为名副其实的地中海里维埃拉——就在巴塞尔市中心。

唾手可及的各色活动、无与伦比的一流公共交通基础设施、安全和稳定的政治局势使得瑞士经常位居生活质量调查排行榜前列。这些都能在巴塞尔地区轻松获得,而艺术文化、生活方式和国际氛围更是锦上添花。因此不足以为奇的是,巴塞尔被瑞士年轻人视作瑞士最具嬉皮士精神和最时尚的地区之一。

我们的服务
Gabriela Güntherodt

您的联系人

Gabriela Güntherodt

Member of the Management Board, Head of International Markets & Promotion

联系我们

投资巴塞尔地区

您的公司正在扩张吗?您正计划立足欧洲和瑞士,借以打入新市场吗?如是,那么巴塞尔地区正是您的理想之选。您将发现让您长久立于不败之地的要素近在咫尺。

众多跨国公司(主要是生命科学领域)确保了真正国际化的商业环境。巴塞尔地区拥有具有国际思维的人才库,整条价值链和各个职能环节都有高技能人才。巴塞尔地处欧洲中部,毗邻法国和德国,因此可以提供良好的商业环境,以及瑞士闻名于世的生活品质。

您想了解在此地区投资的好处吗?我们很乐意为您展示。我们的专家将在贵公司扩张项目的各个阶段为您提出全面而专业的建议。

  • 评估:税务?就业市场?竞争对手?政府许可?产业环境?我们将根据您独特的项目要求,收集巴塞尔地区及瑞士的所有相关信息和数据。
  • 选址:有任何待解决的问题?我们将寻找合适的专家为您答疑解惑。我们会将您介绍给政府机构、行业和法律专家,并在您置业的过程中提供专业支持。
  • 实地考察:您想亲自了解巴塞尔地区吗?我们将完全根据您的需求精心定制一份高效的实地考察计划和行程。
  • 商业开发:您想让公司业务增长提速吗?我们将帮助您建立与本地合作伙伴和机构之间的联系,加快您进驻巴塞尔地区高度多样化商业和创新生态系统的步伐。                                      

我们的服务将免费提供给那些正考虑择址巴塞尔的公司,这也有助于营造充满活力的商业环境。创新和接受新理念的开放心态是巴塞尔地区的悠久传统。我们期待听取您的商业理念,并协助您一开始就取得成功。

Gabriela Güntherodt

您的联系人

Gabriela Güntherodt

Member of the Management Board, Head of International Markets & Promotion

联系我们
Sebastien Meunier

您的联系人

Sebastien Meunier

Member of the Management Board, Head of Innovation & Entrepreneurship


Tel. +41 61 295 50 15

sebastien.notexisting@nodomain.commeunier@baselarea.notexisting@nodomain.comswiss

为创新者牵线搭桥

“为创新者牵线搭桥”服务将创新构想、企业和企业家召集在一起。该服务有两种形式,一种是瑞士巴塞尔大区经济及创新促进局组织的非正式的专家活动,另一种是正式的针对性支持服务,为具体项目提供专家、合作伙伴和融资。我们的专家拥有8000多名创新者组成的强大网络作为后盾。

“为创新者牵线搭桥”服务主要面向以下五大核心主题领域:生命科学、医疗技术、信息与通信技术、生产技术和微技术、纳米技术和材料。每个技术领域都由一名专家专门负责。技术领域经理与行业展开密切合作,制定活动计划,担任项目的联系伙伴,与巴塞尔地区相关研究机构和其他机构培养伙伴关系。

因此,“为创新者牵线搭桥”服务为客户提供了立足于巴塞尔地区、从其多样化创新生态系统受益的理想入口。企业家、创新者和专家每年在逾50场活动上汇聚一堂,定期交流理念和知识,活动形式多种多样:

专题活动:专注于知识转移,为公司、特别是新创公司提供介绍公司和项目的机会,促进巴塞尔地区的创新者进行跨公司和跨学科的经验和知识交流。
研讨会:以拓展新技术应用范围以及发起具体项目和合作企业为目的,通过加强各个公司和学科的专家之间的对话,深度探讨某个主题。
技术与创新圈:运行多年的创新举措,目的是在各个公司和学科所组成的社区中进一步开发主题,以及探索新的市场潜力。

瑞士巴塞尔大区经济及创新促进局的支持创业服务为处于初创阶段的企业提供针对性的活动和服务。

Sebastien Meunier

您的联系人

Sebastien Meunier

Member of the Management Board, Head of Innovation & Entrepreneurship


Tel. +41 61 295 50 15

sebastien.notexisting@nodomain.commeunier@baselarea.notexisting@nodomain.comswiss
Sebastien Meunier

您的联系人

Sebastien Meunier

Member of the Management Board, Head of Innovation & Entrepreneurship

联系我们

支持创业

您正计划创业?这太好了,因为巴塞尔地区以创业为生。瑞士巴塞尔大区经济及创新促进局作为巴塞尔地区创新和外来投资的推进机构,为技术和创新领域的企业家提供支持。

我们服务的核心内容是研讨会及工作坊项目:

  • 创始人课程:扶持性服务的核心内容是我们的研讨会及工作坊项目。“创始人课程”基本套餐的目标群体是计划创业的所有意向方。可在此浏览其他课程的概述:课程概述

    更多服务是专门针对在创新和科技领域有具体项目的初创公司和企业家:
     
  • 企业家研讨会及工作坊:在这些活动中,可以就各种商业问题,例如商业计划、融资、产品开发、定价和知识产权,以及营销与沟通进行深入探讨。这一系列活动专门针对有具体创新项目的初创公司和高科技中小型企业。

    除了培训课程和研讨会之外,瑞士巴塞尔大区经济及创新促进局还提供针对具体项目的单独咨询服务。该咨询服务专门针对创新和科技领域增长潜力巨大的公司和项目。
     
  • 联系与咨询:在初期咨询中,我们的专家将评估对支持的需求,并与专业人士、研究机构或潜在合作伙伴建立联系。
  • 新企业评估:在有专人指导下的流程和单独召开的专家会议中,初创公司和创新型中小企业可以请知名的行业专家、企业家和投资人对其商业项目进行评审。更多信息

    瑞士巴塞尔大区经济及创新促进局的服务涵盖创业的初期阶段。目标是在初期构想到实际创业,再到首个实施计划和融资的过程中,提供宝贵信息和切实的建议。这不仅给予企业家更多安全保障,而且可以显著加快他们实施项目的速度。
Sebastien Meunier

您的联系人

Sebastien Meunier

Member of the Management Board, Head of Innovation & Entrepreneurship

联系我们
Gabriel Schweizer

您的联系人

Gabriel Schweizer

Senior Project Manager Asia


Tel. +41 61 295 50 13

gabriel.notexisting@nodomain.comschweizer@baselarea.notexisting@nodomain.comswiss

进驻中国市场

过去几年中,中国作为商业市场的重要性不断提升。中国不仅是低成本消费品生产的海外目的地,也逐渐成为全球主要销售市场。将业务扩张到中国市场将给予公司巨大的发展潜力,尤其是对于中小型高科技公司而言。但想在中国这样复杂的市场占据一席之地,并非易事。

因此瑞士巴塞尔大区经济及创新促进局为巴塞尔地区(巴塞尔城市州、巴塞尔乡村州和汝拉州)的公司提供全面支持,从初期的市场评估、公司考察,直至寻找到商业合作伙伴。除了提供必要的专业知识外,我们的顾问还拥有良好的本地人脉,这些都是多年来与政商界往来所积累起来的。瑞士巴塞尔大区经济及创新促进局还构建有一个颇具规模的公司和专家网络,他们有与中国打交道的丰富经验,了解所有最新发展趋势。

具体而言,客户公司可以从下列服务中受益:

  • 联系与咨询:提供在中国设立经营业务的基础知识,以及由瑞士全球企业(Switzerland Global Enterprise)的专家提供的一对一的个案咨询。
  • 公司和代表团访问:除正式访问计划外,还可与潜在商业伙伴单独建立联系。
  • 活动:以开发新的共同商业潜力为目标,深化中国与巴塞尔地区的交流。

生命科学公司同样能从与上海张江高科技园区和新建的枫林生命科学园区的合作关系中受益,借此打入中国领先的生命科学枢纽。久经考验的中国本地合作伙伴可以提供支持,协助在上海开展业务(包括产品注册、融资、营销等)和与潜在商业合作伙伴及客户建立联系。

Gabriel Schweizer

您的联系人

Gabriel Schweizer

Senior Project Manager Asia


Tel. +41 61 295 50 13

gabriel.notexisting@nodomain.comschweizer@baselarea.notexisting@nodomain.comswiss

我们的渠道: 活动|博客

report BaselArea.swiss

13 startup projects qualify for the first phase of BaseLaunch

18.09.2017

The BaseLaunch Healthcare Accelerator program from BaselArea.swiss started on September 14. Over 100 applications were received from more than 30 countries, and the selection committee has selected 13 projects to go on to Phase I. Now, the project teams will work with industry experts to further develop their business case over the next three months.

More than 100 projects from over 30 countries were submitted to the BaseLaunch accelerator program from BaselArea.swiss. The submitted projects ranged from therapeutics and diagnostics to digital healthcare and medtech. Instead of 10 as originally planned, the selection committee chose 13 promising projects, which will now proceed to Phase I. "The innovation potential of the project proposals was impressive," says BaseLaunch Selection Committee Chairwoman Trudi Haemmerli, CEO of PerioC Ltd and Managing Director of TruStep Consulting GmbH. “We look forward to seeing how the chosen project teams fine-tune their business cases during Phase I.”

According to Stephan Emmerth, the BaselArea.swiss Business Development Manager for BaseLaunch, the selected projects cover a wide range of objectives: from new approaches for the treatment of diseases such as Alzheimer's or novel immunotherapies to innovative drug delivery methods and next-generation gene therapies for cancer treatment. Other projects focus on new diagnostic procedures for finding cancer biomarkers or revolutionizing the detection of neurological diseases by deploying digital measurement methods.

The development stages of the projects were just as varied. Some projects were submitted by entrepreneurs wishing to establish a company with the support of BaseLaunch. Other projects came from existing startups that had already successfully managed the initial rounds of financing and wanted to further develop the company with the help of BaseLaunch. The founders of these companies and members of project teams also had different professional career histories. Some of the applicants selected for Phase I have many years of R&D experience in the industry; others come from a university background.

"We have chosen the most promising projects. Additionally, selected projects should benefit as much as possible from BaseLaunch and its regional life sciences ecosystem," says Alethia de León, Managing Director of BaseLaunch. “We paid particular attention to a sound scientific and technical foundation, a high level of innovation and the entrepreneurial potential of the founding team.” Alethia also commented on the productive and collaborative selection process with representatives from healthcare partners that included Johnson & Johnson Innovation, Novartis Venture Fund, Pfizer and Roche. "Our discussions during the selection process were very constructive," she says.

The 13 selected startups will have three months from September 14 to develop their business ideas. They will be supported by the BaseLaunch team as well as a number of experienced entrepreneurs and consultants. In this first phase, up to CHF 10,000 will be available for each of the projects. The selection committee will then select three of the Phase I projects to progress to Phase II. This phase lasts for 12 months, with each project receiving funding of up to CHF 250,000. The selected project teams in Phase II will also have access to the BaseLaunch Lab in the Switzerland Innovation Park Basel Area, where they will be expected to achieve important research milestones and further develop their business cases.


Overview of the selected projects:

ABBA Therapeutics develops therapeutic antibodies against novel targets for cancer immunotherapy.

The β-catenin project aims to develop novel therapeutics for the treatment of colorectal, lung, liver, breast, brain and ovarian cancers by removing pathological proteins from the human body.

CellSpring analyzes human cells grown in special 3-Dimensional environments to develop new tools for diagnosing early-stage cancer.

Eyemove strives to detect early-stage neurological diseases through eye-tracking.

Polyneuron Pharmaceuticals is committed to the development of a promising new drug class to treat autoimmune disorders.

The SERI project develops new medicines to treat anxiety and stress related disorders by modulating the activity of cannabinoid molecules in the human body.

SunRegen develops novel drugs for neurodegenerative diseases.

T3 Pharma develops the next generation bacterial cancer therapy.

The mission of T-CURX is to exploit its unique ‘UltraModularCAR’ platform to provide best-in-class immunotherapy.

The mission of TEPTHERA is to offer individualized therapeutic cancer vaccines.

TheraNASH develops precision medicine for fatty liver disease (NASH) - a rising cause of liver cancer world-wide.

VERSAMEB is a regenerative medicine research and development company.

One biotech in stealth mode is developing novel Immuno-Oncology drugs.

report Life Sciences

Roivant Sciences launches Datavant

21.09.2017

event Production Technologies

Swiss eprint – The Swiss Conference on Printed Electronics and Functional Materials

Date: 26.09.2017

Place: Hotel Bildungszentrum 21, Missionsstrasse 21, 4055 Basel

report Precision Medicine

"In Switzerland, we often sell promising technologies too early"

05.09.2017

Ulf Claesson is a "serial entrepreneur". During the past 25 years, he has set up companies that have gone on to become firmly established in the market. In 2012, he joined Clinerion as CEO and shareholder. Since then, the company has positioned itself in the medical data field and recently entered into a partnership with British company Cisiv. Clinerion's software helps recruit patients for clinical trials run by major pharmaceutical companies – in real time. But the competition never sleeps. A growing number of competitors is now appearing, especially in the USA where there is no shortage of risk capital. In this interview for the Innovation Report, Claesson explains how the Basel-based healthtech company plans to maintain its leadership position.

Interview: Thomas Brenzikofer

Mr Claesson, what was behind your decision to get on board with Clinerion?

Ulf Claesson: Clinerion was originally an IT platform with a complicated name. Its founders hit upon the idea of building a large data hub for the pharmaceutical and healthcare industries. That was quite an ambitious idea. I reckon that the WHO or the Bill and Melinda Gates Foundation could possibly manage it. But a small company in Basel? As an IT person, I quickly saw how good the core technology was.  What wasn't clear, however, was the problem that the technology was going to solve. So we started working on that and felt our way slowly but surely towards the patient recruitment use case. Today, we are the only company in the world able to identify in real time from millions of patient data records those patients who are suitable for a specific clinical trial.

So you have aligned the company with a particular niche?

Yes, absolutely. When you are building a company, you must concentrate on solving a genuine problem. Our technology gives the customer clear benefits. Finding patients usually takes months, sometimes years. We cut this to weeks, or less. We ensure that a pharma company, hospital or contract research organisation already before the start of a clinical trial knows exactly where candidate patients are located and exactly how many there are. Depending on the goal, the study protocol can then be optimised as required. Because we avoid guesswork and identify genuine patients who meet the study criteria in this very moment, the study design is robust and risk is minimised. Not only that, but a study sponsor knows exactly where and how many of his "sites" he must place. Real-time information is particularly valuable for this. As soon as I activate a study protocol, the doctors involved are notified and can call their patients in.

Is it easy to convince hospitals to collaborate with Clinerion?

We were rather naive about this at first. From an IT perspective, it makes sense to do everything in the cloud. That is exactly what we tried to do, but most people were negative about it. We also found that attitudes to data protection, as well as the regulations themselves, vary considerably from one country to the next. These factors make a cloud solution virtually impossible to implement. Today, we are installing a hardware appliance within a hospital's IT infrastructure. The data therefore remains exactly where it is collected and it is as secure as all other patient data. We can also only access consolidated and aggregated meta information, which earns us the trust of decision-makers and the people using the system.

What exactly motivates hospitals to disclose their data?

We all basically share the same objective of providing relevant patients with drugs as soon as possible. We play a role in achieving this. The university hospitals are carrying out research to some extent for their own interests. We help them to carry out their internal studies more quickly. The pharmaceutical companies remunerate the hospitals for each patient who participates in a study. The doctors feel that participating in interesting studies is important. In our experience, the number of studies that hospitals are offered increases significantly as soon as they start working with us.

How many patients do you currently have access to?

We have access to 35 million patients via the hospitals. And we certainly need that many. The numbers can start dwindling rapidly depending on the symptoms you are searching for.

You operate mainly in emerging markets such as Brazil and Turkey.  Why is that?

With the exception of the UK, Europe is more cautious about taking part in clinical trials. By 2020, Turkey expects to have increased the EUR 50 million turn-over in clinical trials in 2014 to EUR 1.5 billion. In Brazil, they are even changing the law to make it easier for pharmaceutical companies to carry out more studies in the future. In clinical trials, it is important for all participating patients to receive the same standard of care. Participants in trials might therefore receive better care than usual. This applies to some countries in Eastern Europe, for example. For some patients, this can be an incentive.

Does your data acquisition prioritise emerging markets?

No, not exclusively. We are also well positioned in a number of European countries. But we can certainly do better. We would also like to expand our presence in India and Taiwan, for example. Great Britain is a key focus for us and our partnership with Cisiv will help here. We recently entered into a partnership with this UK company. Cisiv’s platform complements our screening programme perfectly.

It sounds like a data contest. How close is your main competition?

There are three competitors. But we are the only ones able to provide real-time results. Our competition in the USA, however, has access to much more capital. At the last investment round, one of our competitors raised 32 million dollars.

Do you find it difficult to compete with that?

It is certainly difficult for an ICT start-up in Switzerland to obtain those kinds of amounts. We are not completely dependent on external investment, however. We have a very loyal shareholder base and have sufficient funding, even though we are still a long way from being profitable.

Could a sale be on the cards?

Our vision is to provide patients with medicines. If we see that we can achieve this goal more quickly, we would be willing to consider it. But selling is not currently under consideration. I have already founded a number of companies. Some were sold too early, even though we could still have helped them progress through one or more growth phases. I am convinced that Clinerion will succeed in that regard.

Do you consider the lack of growth financing to be a problem for the Swiss start-up scene?

Most certainly. Good technologies tend to be sold off too early because their owners cannot find the money they need for the next major milestone, typically for the global expansion phase.  

What do you suggest?

Imitating Silicon Valley will get us nowhere. Also because costs there are unacceptably high at the moment. We really need to focus on our strengths. Just to give you one example: twice as many startups are established at ETH Zurich each year than at UC Berkeley. When universities foster a supportive environment, a start-up community develops all on its own. The students I meet at ETH are ambitious and full of energy. I also note, however, that many Swiss students prefer the security of working in a large corporation. We need a greater willingness to accept risk. We need to work on it.

How do you see innovation hub Basel?

We have good access to the sector here, and we can also recruit staff from neighbouring Germany. The labour market is therefore less competitive than in Zurich for example. We feel right at home here in Basel.

 

About Ulf Claesson
Ulf Claesson studied production technology at Chalmers University in Gothenburg and also gained a management degree at the University of St. Gallen. He worked for IBM and Hewlett-Packard, established spin-offs for various companies, and founded his own start-ups. In his lecture on "Technology Entrepreneurship" he passes on his experience as a "serial entrepreneur" to students at ETH. He is a member of the board of directors of various companies, the Foundation Board Director of the AO Foundation, and has been the CEO of Clinerion since 2012.

report Production Technologies

The Swiss Conference on Printed Electronics and Functional Materials

21.09.2017

event Innovation

Growth by Collaborations – How to find Partners for Innovation and Business

Date: 26.09.2017

Place: Technologie Park Basel, Hochbergerstrasse 60C, 4057 Basel

report BaselArea.swiss

"I want to turn innovative research into new drugs"

04.07.2017

Each year some 250,000 patients develop a type of cancer because of faulty communication between cells. This malfunction occurs in what is known as the NOTCH signal path. There are currently no effective treatments – but this is set to change. Cellestia Biotech AG is developing an innovative drug against this type of cancer by using a novel active ingredient that selectively attacks the malfunctioning cell communication. The drug could be used to treat leukaemia, lymphomas and solid tumours such as breast cancer.

In 2014 Professor Freddy Radtke and Dr Rajwinder Lehal, who had dealt with this subject in his dissertation, founded the company Cellestia Biotech AG. In 2015, an experienced team of pharmacology and oncology development specialists led by Michael Bauer came on board, investing in Cellestia as co-founders. Bauer and his team had previously spent several years examining various projects in an effort to help shape the development of such a start-up company. We spoke with him about the risks and implications of founding a company.

Interview: Stephan Emmerth

Mr Bauer, how long did you have to look before you found a project you wanted to invest?

Michael Bauer: Over the course of many years and alongside my regular jobs, I and my colleagues examined, evaluated and rejected a number of projects – sometimes more intensively, sometimes less. Some of the projects were great, some being unbelievably innovative. However, something always led us not to pursue a project in the end.

The search did not just cost you a lot of time, but also a lot of money as you have to conduct due diligence every time.

We of course had to put effort into the search. You could say that we identified, examined and evaluated projects acting similar to a small venture fund. Thanks to the make-up of our team, we were able to undertake many of the tasks ourselves, at times bringing in experts. There were many instances when specialists from our network assisted us. There was a considerable amount of good will. To some extent we footed the bill ourselves.

Why did this not work out before Cellestia?

A number of conditions have to be met. The basis is of course excellent, innovative research results protected by patents. Also important are ownership rights to the inventions and reasonable licencing terms. Finally, there has to be agreement on the expectations of the people involved in the project. We have experienced pretty much everything. Many times it emerged over the course of the investigation that, for example, the research data was not quite so convincing as had initially been presented. Or the expectations with respect to the licencing conditions were too far apart. In one project, they wanted to sell us patents that had expired. It often happens that the scientists have unrealistic ideas about the value of their project. One retired professor who had tried in vain for many years to finance his company expected us to try for five per cent of the shares. This is of course not the basis for a partnership.

Juggling research and entrepreneurship is a big challenge, isn’t it?

It is necessary to develop an understanding of the relations and contributions of the various partners involved in such a project, each of who have very different personal risks. On the one hand, there is some 20 years of basic research behind Cellestia, 11 of which were at the EPFL. Rajwinder Lehal has been working concretely on this project for the past nine years, initially as part of his dissertation, then as a post-doc and since 2014 as Chief Scientific Officer. We respect this history from the management team and are happy to have access to the resulting knowledge. At the same time, the inventor’s side has to have regard for the entire expenditure: some five million of public funds were invested over the years at the EPFL. However, it could take hundreds of millions until a product comes onto the market. Moreover, the path from the first successful experiment in lab animals until a drug is approved for human use is long. Altogether, the cost of research could be marginal in comparison to the development and marketing, amounting to only a few per cent. And the development costs are paid for by the investors, who need the investment to pay off. All of these factors have to be considered and respected in a partnership. This worked with our team.

You have many years of industrial experience. What attracted you to the entrepreneurship?

The challenge of turning ground breaking inventions into products attracted me. I consider myself a product developer and had wanted to start a company even as a student. Looking back, I have to say that I am lucky to have gained nearly 20 years of professional experience in product development as it is important to be able to understand and appreciate just how complex the challenges are in product development in life sciences and pharma. This wealth of experience also helps you understand where your own knowledge ends and when experts have to be brought on board to be able to successfully advance a project or a company.

What was the incubation from first contact until you joined as co-founder at Cellestia like?

The current Chief Scientific Officer, Rajwinder Lehal, and I had been in regular contact with each other for a number of years. At that time, however, the project was not advanced enough to establish a company. Initially, Professor Radtke, Rajwinder Lehal and Maximilien Murone founded Cellestia in 2014. We met a few times in summer 2015 with the Lausanne research and founder team at i-net, the predecessor of BaselArea.swiss. Things moved quickly from there. In just a few meetings, we were able to evaluate the project and develop a good personal understanding, which for me and my partners was very important if we were to invest in Cellestia. We could agree on matters quickly, more or less by handshake. Then came the necessary contracts and in November we were already listed in the commercial register. Our lawyer and co-founder Ralf Rosenow saw to the formalities. We decided to move the headquarters from Lausanne to Basel but to leave the research activities in Lausanne, resulting in a sort of transcantonal partnership.

Why move the headquarters to Basel?

For us, the most important argument in favour of Basel was access to talent and resources for product development, resulting from the proximity to leading pharmaceutical companies such as Novartis, Roche, Actelion and many others. Such access to experienced development specialists is more difficult in Lausanne. In addition, our co-founder Roger Meier and other colleagues already have an active investor network in Basel with an affinity to the sector and Basel itself. We did not have such access in Zurich or Geneva at the beginning. I personally also like the quality of work and life in Basel. The city is of a manageable size yet international, with diverse cultural offerings. Furthermore, the Basel airport has excellent connections – you are in the middle of Europe and in just one to two hours you’re practically anywhere Europe, be it London, Berlin or Barcelona. Lausanne, on the other hand, has in its favour the outstanding academic environment with the EPFL and the Swiss Institute for Experimental Cancer Research. Here, too, there is an excellent environment for start-ups, but in our opinion more toward engineering and technical disciplines or medicine technology. Many companies are founded each year at the EPFL and the innovation potential is enormous, but Cellestia is the first company founded at the EPFL that seeks to bring a drug to clinical development. We are happy to be able to combine the positive elements of both regions via what is now an established approach with two locations.

Which pre-conditions were decisive enough that you ended up collaborating and founding the company?

Actually, everything was right from the very beginning. First of all, the personal atmosphere between the people involved has to be right. This was also the basis in coming to a fair agreement for all co-founders with respect to understanding the evaluation and allocating the respective shares in the company at the time it was founded. On the other hand, it was of course crucial that the substantive examination of the project – as concerns both the scientific basis and the quality of the data – and the examination of the patent as well as license conditions of the EPFL were positive. Also important to us was that the risk profile is manageable, i.e. there is a good balance between innovation and reference to the research already carried out.

How will Cellestia develop further operationally?

Cellestia already has a long history, starting with the research activities at the EPFL. When the management team was expanded in 2015, other co-founders joined at the same time that I did: Dirk Weber as Chief Medical Officer, as well as the already mentioned co-founders Ralf Rosenow and Roger Meier. Cellestia now has six employees. Then there are the numerous service and consulting mandates, which complement our internal resources as needed. If you take into consideration external services, I reckon there are now well over 100 people involved in Cellestia. We expect that we will continue to grow in the direction of clinical development as our first project progresses and further expand the team. Moreover, we would like to develop additional products in our pipeline as soon as possible. This will definitely require additional financial resources. The Board of Directors will also develop further, expanding and adapting with each financing round in order to properly represent new investors. Research work is increasingly being carried out by external services providers, and at the same time continuing in the laboratory of Professor Freddy Radtke at the EPFL. We are currently setting up new framework agreements with the EPFL concerning the further use of their infrastructure. The flexibility there is very helpful for us.

What are the next milestones?

A key milestone is the treatment of the first cancer patients. We hope to be able to treat the first patients in October.

How are the clinical studies organised?

The course of a clinical trial for new drugs is strictly regulated. In the Phase I study, the compatibility of the active ingredient is first examined. This is when we treat patients who are suffering from a form of cancer in which NOTCH most likely plays a role. In the following Phase II study, the efficacy of our drug is researched in different types of cancer. This is when we select patients in whom activation of the NOTCH signal path is detected with a Cellestia diagnostic method. The therapeutic benefit for these patients is therefore very likely.

Have there been any surprises so far?

No, not really, because we have considered everything. Or yes, but pleasant surprises: due to the considerable amount of preparatory work, we were already quite certain with respect to the effect mechanism. It has now finally been possible to detect the precise binding mechanism of the drug, which confirmed all former studies. This is also the basis for significantly expanding the programme. We can now build a new platform on whose basis we can generate new drugs for new indications. In addition, it was not that easy to manufacture the drug in large quantities and in a high quality. Innovative steps were needed, which ultimately leads to a patent.

What do you have in mind for the next five years?

We are very optimistic about Cellestia’s prospects for success and are planning the next couple of years in detail. We of course also have a plan for the overall development over the next five years, but as experience shows, such plans always change with the results obtained. This is also the fascination and challenge in medication development – it does not allow you to plan everything in detail, and you have to respond flexibly to new results. This also applies to possible setbacks, of course. It is important to have sufficient reserves to deal with these and resolve them. Thanks to the successful financing rounds that we could close in January 2017, we are in a position to begin with Phase I while at the same time pursue further financing.

Who has invested in Cellestia so far?

The first investors after the deposit of the initial capital were predominantly many of our advisors, i.e. experts who are familiar with the sector as well as private people involved in life sciences and the pharma sector as investors. Around one-third of the shareholders are experts from the pharma and life sciences setting. Over the course of the Series A, B and C financing rounds, larger investments from family offices also came. The first institutional investor, the PPF Group, invested after its own, extensive due diligence that was conducted by experts from Sotio. So far, we’ve been able to mobilise a total of CHF 8 million to drive product development at Cellestia. In preparation of the next financing round, we are in talks with private investors, venture funds and pharmaceutical companies. We are confident that we will be able to win good partners for Cellestia’s next phase. The right combination of partnerships and financing is important. We need strong partners on board to give patients access to our medications quickly.


About
Michael Bauer (born 1966) has been CEO at Cellestia since November 2015. He studied chemistry at the University of Hamburg and completed his doctoral in biotechology from 1994 to 1997 at the Hamburg-Harburg University of Technology. After working in metabolic research at Zeneca in England, he moved to Syngenta in Basel in 2001 where he worked as Global Regulatory Affairs Manager in project and portfolio management. From 2007 to 2009 he was a project leader at Arpida, a biotech firm in the field of antibiotics development. From 2009 to 2012 he was a Global Program Manager at Novartis where he led global development projects in the field of oncology and brought a range of products to clinical development. From 2012 to 2015 he was the Head of Clinical Development at Polyphor.

report Life Sciences

Keith A. Katkin named CEO of Urovant

19.09.2017

event Supporting Entrepreneurs

Workshop Pitching

Date: 28.09.2017

Place: Startup Academy, Picassoplatz 4, 4052 Basel

report Invest in Basel region

Roivant is creating a buzz in Basel

13.06.2017

Roivant Sciences, a fast-growing life sciences company from the US, recently opened its global headquarters in Basel. In celebration of their newly established location, Roivant, together with BaselArea.swiss, invited stakeholders from the life sciences sector to “Halle 7, Gundeldingerfeld” in Basel on June 8th 2017 for a panel discussion on the future of healthcare.

More than 150 guests were interested in hearing this success story first-hand from Roivant Sciences’ founder and CEO, Vivek Ramaswamy. Ramaswamy, a member of the renowned “Forbes 30 Under 30” list and also named a “prodigy” by Forbes magazine for the biggest biotech IPO in US history, gave a trenchant keynote speech before being joined by a panel of experts from Basel’s pharma and biotech industry.

Ramaswamy explained his mission: “We concentrate on promising science and passionate people to systematically reduce the time, cost and risk of bringing new medicines to market”, he said. Roivant Sciences buys and develops drugs that are shelved by other large pharmaceutical companies, and that are stuck in the middle of the drug development traffic within the organization. Ramaswamy’s mission is to create an “alternative highway” by bringing together top talent in drug development and other industries and focus on those assets within lean and dynamic structures. Ramaswamy is certain that data will make the difference in bringing drugs speedily to market.

Roivant Sciences is the umbrella company of five (and the number growing!) late-stage biopharma companies in different therapeutic areas: Axovant tackles dementia, Dermavant deals with dermatology, Myovant focuses on women’s health, Urovant concentrates on urology and Enzyvant develops therapies for patients with rare diseases. All Roivant-family companies can tap into standard capabilities built at Roivant, while each company can develop capabilities of their own to address their specific market requirements.

Settling in Basel without red tape

In his speech, Ramaswamy also made a case for Basel as a headquarters location: “Different nationalities are coming together in this place, three different languages are spoken on the street.” Although relatively small, Basel-Stadt and Basel-Landschaft would be “punching way above their weight”. He also mentioned the thriving biotech scene and the deep humanistic tradition in Basel. In addition, Ramaswamy thanked the Basel authorities for lowering barriers in setting up a business: “There was no red tape. They made setting up here a pleasure.”

During the subsequent panel discussion, Vas Narashimhan, Global Head of Drug Development and Chief Medical Officer at Novartis, Jonathan Knowles, Chairman of the board of directors at Immunocore Limited, David Hung, CEO of Axovant and Vivek Ramaswamy discussed the future of healthcare. Moderated by Alethia de Léon from BaseLaunch, the conversation included topics such as data collection, and critical questions about the current challenges and opportunities of the pharma industry were raised. Big data and biomarkers were some of the highlighted topics as potentially helping to address some of the R&D productivity issues the industry is currently facing. 

report Precision Medicine

Patient Data – Faster but with Respect and Trust

14.09.2017

event Supporting Entrepreneurs

Workshop Mixed Management Pickles

Date: 29.09.2017

report BaselArea.swiss

BaselArea.swiss got off to a successful start

08.06.2017

In its first annual report, the newly formed BaselArea.swiss can look back on a successful 2016. The joint initiative for innovation and economic promotion by the cantons of Basel-Stadt, Basel-Landschaft and Jura succeeded in growing in all areas. It provided assistance to 36 companies moving to the region, which corresponds to a 50% increase over the previous year. In the area of innovation promotion, over 4,000 participants attended 80 events, expanding the regional network from 8,000 to 13,000 innovators and experts. The services provided by BaselArea.swiss were also actively used to promote start-up projects, contributing to 43 companies being founded.

With a 50% increase over the previous year, the Basel region recorded the biggest growth across Switzerland with the number of new companies to the region. The economic promotion team at BaselArea.swiss advised and assisted 31 foreign and 5 domestic companies relocate to the Basel region. 14 companies came from the US and Europe each, and 3 from Asia. 19 of the new companies to the region are active in the life sciences.

“The consolidation of economic promotion and innovation/start-up promotion under one roof is paying off. By focussing on the strengths of the economic region, the location was able to clearly gain importance as a significant innovation hub in the life sciences and related technologies,” says Christoph Klöpper, CEO of BaselArea.swiss.

Growing network of innovators and experts

BaselArea.swiss succeeded in significantly expanding the network of innovators and experts in 2016, growing from 8,500 people at the end of 2015 to more than 13,000 people at the end of 2016. This puts BaselArea.swiss in a position to better assist clients with respect to relocations as well as innovation and expansion projects by providing them with targeted communication of knowledge and partnerships. The more than 80 events organized by BaselArea.swiss – attended by over 4,000 participants – made a key contribution to the expansion of the network. In addition, BaselArea.swiss supported start-ups and companies in more than 180 individual consultations, including initiating cooperation in research and development as well as in establishing contacts to potential customers and investors. In total, BaselArea.swiss provided assistance that resulted in 43 companies being founded.

BaselArea.swiss grew out of the merger of i-net innovation networks, the economic promotion agency BaselArea and the China Business Platform, and began its operational activities at the beginning of 2016 under the new brand BaselArea.swiss with a unified services portfolio and newly launched website. Its entrepreneurial profile has also been strengthened: industry representatives now form the majority of the Board of Directors, which is chaired by Domenico Scala and is responsible for strategic orientation.

report ICT

Genedata simplifies cell analysis

14.09.2017

event Life Sciences

Molecular Partners: Road to IPO and beyond

Date: 03.10.2017

Place: Halle 7, Gundeldingerfeld, Dornacherstrasse 192, 4053 Basel

report BaselArea.swiss

A molecular assembly line to cure the body

08.06.2017

Imagine that certain forms of blindness could be cured. Or imagine that the body itself could produce a cure for some of its own diseases. These may be just some of the results of the National Centre of Competence in Research Molecular Systems Engineering (NCCR MSE). Its long-term goals are to create molecular systems and factories for the production of high added-value chemicals and develop cellular systems for new applications in medical diagnostics, therapy and treatment. Director Thomas Ward is aiming high: He wants to make Basel the leading hub for the next European flagship project. At stake: one billion euro.

Interview: Ralf Dümpelmann

Thomas Ward, you are the director of the NCCR MSE. How did you end up in this position?

Thomas Ward: During my work at the University of Neuchâtel we became curious about artificial metalloenzymes. For instance, we could take ruthenium ion that nature does not have much of at its disposal, and incorporate it in a protein to yield an artificial metalloenzyme. Pursuing this curiosity driven pathway, my group became more and more interested in biological questions. Ultimately I wanted to collaborate with molecular biologists – and this is one of the main reasons why I moved to Basel. When I arrived here nine years ago, the ETH Department of Biosystems Science and Engineering (D-BSSE) had just moved to Basel. That led professor Wolfgang Meier, then head of the Department of Chemistry at our university, to initiate talks with the D-BSSE which were very productive. In the end, he and co-director professor Daniel Müller set out for a National Centre of Competence and Research that ultimately got funded by the Swiss National Science Foundation (SNSF).

What was the goal when starting the NCCR?

Wolfgang Meier and Daniel Müller saw the opportunity to start a collaboration between biologists who relied quite heavily on chemistry and chemists who can provide the required chemical building blocks to address challenging biological questions. This is scientifically a very unique match. In my view this is also reflected in the most important aspect in the title of our NCCR – molecular systems engineering – namely the systems aspect.

Do you build artificial biological systems with the help of chemistry?

At the end of the road, we want to reproduce the properties and the complexity of a living system. There are two ways to get there. The chemical way is to take a compartment, put objects inside one by one and see what evolves. That is the bottom-up approach. On the other hand, a biologist takes a complex system and knocks out components, one at a time. In doing so, biologists focus on computing a system. And they are doing this very well. They can control things, even without fully understanding the molecular details of such systems. These two approaches meet at some point, and that is where our NCCR comes into play.

What could a potential end result look like? A small golem?

If you take the definition of what is life, there are a few features that we are definitely not trying to mimic. We are rather focusing on an artificial organelle, something that you could introduce into a living system and which would work in a living system, but which does not have all the features of a living system itself. I like to call such components molecular prostheses. It is like an artificial Lego block that fits into living systems. There we are already quite advanced.

Can you explain how the work of the NCCR is structured?

The network is planned to work over twelve years, split in three phases. There are roughly 30 groups associated with this NRCC, with some 20 in Basel. When there is somebody outside of Basel who has a competence that we need, they can be integrated to the network. That might be people in the Paul Scherrer Institute or at the University of Bern, for instance.
We are now approaching the end of the first phase of four years. The first step for us as chemists is to synthesise and assemble molecules into modules, an assembly of several molecules. For example, Sven Panke at the D-BSSE and myself synthesise artificial enzymes. Daniel Müller of the D-BSSE on the other hand manipulates pore proteins which allow to control the trafficking of substrates and products in and out of a cell. The goal is assemble an artificial organelle containing two or three enzymes and to introduce this prosthesis inside a cell. With that we can complement the natural metabolism of a cell with an artificial metabolism to produce new chemicals. At the end of the first phase, we ideally want to have solved the module’s problem. In the second and third phase, we can then focus on creating molecular factories and cellular systems.
Ultimately, a chemical factory could produce something that could be useful and a cellular system could be used to cure a disease. For both of these goals, you need a molecular assembly line, much in the spirit of what Henry Ford developed in the early twentieth Century, but at a molecular scale.

Do you already get a stable system out of these assembly lines?

Yes. The question is, however, how stable and for how long. We have systems that function in a cell for two weeks. Whether this is enough to cure a disease remains to be demonstrated.

What benefits may come out of it?

Our aim is to change the way biology and chemistry work in the long term. It is a risky strategy, but with a potentially high payoff.

What would be the high payoff?

You put a molecular or cellular system in the body and it treats or cures a disease.

When will that be feasible?

There are two systems, which are already very well advanced. Both were initiated and funded by the NCCR. Botond Roska of the Friedrich Miescher Institute for Biomedical Research has developed a system that can be injected into the eye to regain vision. This system will enter clinical trials in Winter 2017. It is based on genetic engineering, where you have to inject DNA so that your eye starts to produce pigments again. The other one is aimed at curing diabetes. Your fat cells are re-programmed into cells that are capable of producing insulin. They are then injected into your body and allow you to autonomously produce insulin when the body needs it.

Will these ideas be used in start-ups?

Yes. There are already two start-ups that were created in the past three years. The diabetes treatment is also seriously being looked at for a start-up. The SNSF wants to see things like that. It wants us to bring our research to an advanced stage.

You are organising the International Conference on Molecular Systems Engineering in Basel at the end of August. What is its main goal?

It is a challenge to organise such a conference because people who attend conferences like to talk to specialists in their fields. In our case, we want to apply our approach to a number of different fields. There will be outstanding speakers, but we have to convince people that it is worth looking at the subject from a broader perspective. The good news is that there are similar projects in Europe, in the Netherlands and in Germany. We will have a pre-conference, where graduate students from these other projects can exchange experience and ideas with students from the NCCR.

Is the conference a step to the European level?

Four years ago, the EU funded so called flagship projects. One of them was the Graphene project in Manchester, the other one the Human Brain project at the EPFL in Lausanne. These flagships have a budget of a billion euro. It seems that Europe will have a second round of such flagship projects in a few years. Our aim is to apply for the funding together with our partners in Germany and the Netherlands which would ensure the development of molecular systems engineering at a European level in the future.

In unique events the conference combines art and research. What is the idea behind this special mix?

It is about communication and ethics. We asked ourselves how we can talk about our research as it is quite complex for lay people to understand. One answer is to interact closely with artists and see if they can show their interpretation of what we do, and hopefully this would speak more to the public. We worked with artists hoping that they might rise interest in our research. Furthermore we can engage the public in a dialogue about ethical questions.

When will this dialogue start?

At our conference the argovia philharmonic will present a composition based on illustrations and videos we have provided them with. On the same day, we will also have a public ethics debate. We have brought in an editor of “Science” who will animate the debate and there will be three people debating. We hope one of them will be a bioethics officer of the Pontifical Academy for Life, the two others will be scientists.

What was for you the scientifically most exciting aspect of this NCCR?

When we started, we had a very broad approach and we had quite a number of curiosity-driven research projects. Without it, we would not have come as far as we did in these three years. For the second phase – we have just submitted the pre-proposal – we are much more focused.

What do you hope to achieve at the end of the NCCR?

If we only get one product in use this would already be a very nice achievement. Imagine, for example, that we could say: This NCCR has cured some forms of blindness.

About:
Professor Thomas Ward, born in 1964 in Fribourg, is the director of the NCCR Molecular Systems Engineering. He heads the Ward Group at the Department of Chemistry of the University of Basel. The group’s research focuses on the exploitation of proteins as a host for organometallic moieties with applications in catalysis as well as in nano-biotechnology.
Ward studied organic chemistry at the University of Fribourg. He wrote his PhD thesis at ETH Zurich. He did a first postdoc with Roald Hoffmann at Cornell University in theory and then a second postdoc in Lausanne. He was then awarded an A. Werner Fellowship and moved to Bern where he obtained his habilitation. He moved to Neuchâtel in 2000 and to Basel in 2008. He was awarded a prestigious ERC advanced grant in 2016 and the 2017 Royal Society of Chemistry award in Bioinorganic chemistry.

report ICT

BC Platforms launches analytics tool

13.09.2017

event Production Technologies

La réalité augmentée au service de l'économie

Date: 05.10.2017

Place: Campus Strate J, HES-S0, Route de Moutier 14, 2800 Delémont